Over the years, ALS Canada has committed valuable research funding to better understand the genetics of ALS and finding novel gene therapies.

Project MinE

Project MinE is a pioneering and collaborative project that aims to understand the genetic basis of ALS and to ultimately find a cure for this devastating disease. It aims to analyze the whole genome sequence of at least 15,000 people living with ALS and 7,500 healthy controls. A whole genome sequence provides the entire set of someone’s DNA. Most ALS genetic studies to date have analyzed a portion of the DNA that only represents two per cent of their genome, making Project MinE a database of unprecedented power.

ALS Canada made a promise to contribute to the funding of 1,000 DNA samples. To date, we have provided more than 800 samples.

ALS Canada’s Research Program will continue to support Project MinE in its work towards unraveling ALS.

ALS Compute

ALS Compute aims to centralize all global ALS/FTD whole genome data on a single storage platform with minimal barriers to researchers for access and study. The goal is to facilitate the fastest possible use of global genetic information to discover new avenues of understanding and treating ALS/FTD. ALS Canada is supportive of the Open Science nature of ALS Compute and encourages Canadian and non-Canadian researchers to submit any of their data not already present in the database.

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