Research Update

* Neurofilament light (NfL) is a protein released when neurons are damaged and can be detected in the cerebrospinal fluid and blood. In ALS, higher NfL levels are generally associated with more rapid disease progression, at a group level. In clinical…

Our bimonthly Fundamental Research Update keeps you informed about the latest advances in lab-based ALS research. We break down new studies using cellular and animal models, highlight progress on promising preclinical targets, breakdown trending research news, and showcase Canadian led science.  For other news on clinical research and trials, read our Clinical Research & Trials Updates.  ALS…

PrimeC, an investigational therapy by NeuroSense Therapeutics, combines two existing prescription drugs: the antibiotic ciprofloxacin and the anti‑inflammatory drug celecoxib. Together, they are thought to target three biological processes linked to ALS: inflammation in the brain, abnormal microRNA activity (small RNA molecules that help regulate…

Our bimonthly Clinical Research & Trials Update keeps you up to date on what’s happening in ALS clinical research. We unpack trial press releases, flag upcoming studies, and highlight important new publications, including care guidelines, long-term therapy data, and off-label treatment insights.  For other news on…

Our bimonthly Fundamental Research Update keeps you informed about the latest advances in lab-based ALS research. We break down new studies using cellular and animal models, highlight progress on promising preclinical targets, breakdown trending research news, and showcase Canadian led science.  For other news on clinical research and trials, read our Clinical Research & Trials Updates.  ALS…

Our bimonthly Clinical Research & Trials Update keeps you up to date on what’s happening in ALS clinical research. We unpack trial press releases, flag upcoming studies, and highlight important new publications, including care guidelines, long-term therapy data, and off…

ALS researchers worldwide continue to build on existing work and make new discoveries in the hopes of a world free of ALS. In the November 2025 Research Update, explore new insights into clinical trials, biomarkers, and strategies for understanding and…

ALS researchers worldwide continue to build upon existing work and make new discoveries in the hopes of a world free of ALS. In the August 2025 Research Update, explore new insights into ALS treatments, biomarker detection, environmental factors, genetics, and…